High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy

High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy

ABSTRACT Microbial diversity in the cystic fibrosis (CF) lung decreases over decades as pathogenic bacteria such as Pseudomonas aeruginosa take over. The dynamics of the CF microbiome and metabolome over shorter time frames, however, remain poorly studied. Here, we analyze paired microbiome and meta...

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Bibliographic Details
Main Authors: Ruma Raghuvanshi, Karla Vasco, Yoshiki Vázquez-Baeza, Lingjing Jiang, James T. Morton, Danxun Li, Antonio Gonzalez, Lindsay DeRight Goldasich, Gregory Humphrey, Gail Ackermann, Austin D. Swafford, Douglas Conrad, Rob Knight, Pieter C. Dorrestein, Robert A. Quinn
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
cystic fibrosis
microbiome
antibiotics
metabolome
Microbiology
QR1-502
Online Access:https://doaj.org/article/44dcf055fdac407cb29d702c06bbc3b3
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https://doaj.org/article/44dcf055fdac407cb29d702c06bbc3b3

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