The GPR171 pathway suppresses T cell activation and limits antitumor immunity

The GPR171 pathway suppresses T cell activation and limits antitumor immunity

Proliferative and effector functions of T cells are determined by T cell receptor signalling and modulated by activator and inhibitory co-receptors. Authors report here that the G-protein-coupled receptor GPR171 functions as a co-inhibitor of T cell signalling and might serve as a target for cancer...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yuki Fujiwara, Robert J. Torphy, Yi Sun, Emily N. Miller, Felix Ho, Nicholas Borcherding, Tuoqi Wu, Raul M. Torres, Weizhou Zhang, Richard D. Schulick, Yuwen Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/4515b28636ca4c3b83d2b6c3169e1d1a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares