How RNA transcripts coordinate DNA recombination and repair

Homologous recombination (HR) typically uses DNA as a donor template to accurately repair DNA breaks. Here, the authors elucidate two mechanisms by which RAD52 uses RNA as a template for HR: one involving RNA-mediated synapsis of a homologous DNA break, and the other involving reverse transcriptase...

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Autores principales: Shane McDevitt, Timur Rusanov, Tatiana Kent, Gurushankar Chandramouly, Richard T. Pomerantz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/451d01082cb64f63ab8102cbd1ccb3ed
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