How RNA transcripts coordinate DNA recombination and repair

Homologous recombination (HR) typically uses DNA as a donor template to accurately repair DNA breaks. Here, the authors elucidate two mechanisms by which RAD52 uses RNA as a template for HR: one involving RNA-mediated synapsis of a homologous DNA break, and the other involving reverse transcriptase...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shane McDevitt, Timur Rusanov, Tatiana Kent, Gurushankar Chandramouly, Richard T. Pomerantz
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/451d01082cb64f63ab8102cbd1ccb3ed
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!