Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

Therapeutic antibodies against flaviviruses often promote neutralization by targeting the envelope protein of the virion. However, this approach is hindered by a possible concern for antibody-dependent enhancement of infection and paradoxical worsening of disease.

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Auteurs principaux: Alex W. Wessel, Michael P. Doyle, Taylor B. Engdahl, Jessica Rodriguez, James E. Crowe, Michael S. Diamond
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
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Accès en ligne:https://doaj.org/article/452803504505489b8c84cd953cbd6230
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