Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection
Therapeutic antibodies against flaviviruses often promote neutralization by targeting the envelope protein of the virion. However, this approach is hindered by a possible concern for antibody-dependent enhancement of infection and paradoxical worsening of disease.
Guardado en:
Autores principales: | Alex W. Wessel, Michael P. Doyle, Taylor B. Engdahl, Jessica Rodriguez, James E. Crowe, Michael S. Diamond |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/452803504505489b8c84cd953cbd6230 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies.
por: Lindsay Crickard, et al.
Publicado: (2012) -
Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus.
por: Junyun He, et al.
Publicado: (2014) -
Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus
por: Estefania Fernandez, et al.
Publicado: (2018) -
THERAPEUTIC EFFICACY OF MONOCLONAL ANTIBODIES AGAINST LETHAL TOXIN OF BACILLUS ANTHRACIS IN A MOUSE MODEL
por: Ia. O. Muntian, et al.
Publicado: (2018) -
Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection
por: Yen-Chung Lai, et al.
Publicado: (2017)