The Chemical Fluctuation Theorem governing gene expression

A unified framework to understand gene expression noise is still lacking. Here the authors derive a universal theorem relating the biological noise with dynamics of birth and death processes and present a model of transcription dynamics, allowing analytical prediction of the dependence of mRNA noise...

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Autores principales: Seong Jun Park, Sanggeun Song, Gil-Suk Yang, Philip M. Kim, Sangwoon Yoon, Ji-Hyun Kim, Jaeyoung Sung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/453b0f4d9a3147b59f1f6680d93343c0
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