The Chemical Fluctuation Theorem governing gene expression

The Chemical Fluctuation Theorem governing gene expression

A unified framework to understand gene expression noise is still lacking. Here the authors derive a universal theorem relating the biological noise with dynamics of birth and death processes and present a model of transcription dynamics, allowing analytical prediction of the dependence of mRNA noise...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Seong Jun Park, Sanggeun Song, Gil-Suk Yang, Philip M. Kim, Sangwoon Yoon, Ji-Hyun Kim, Jaeyoung Sung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/453b0f4d9a3147b59f1f6680d93343c0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:453b0f4d9a3147b59f1f6680d93343c0
record_format dspace
spelling oai:doaj.org-article:453b0f4d9a3147b59f1f6680d93343c02021-12-02T16:49:39ZThe Chemical Fluctuation Theorem governing gene expression10.1038/s41467-017-02737-02041-1723https://doaj.org/article/453b0f4d9a3147b59f1f6680d93343c02018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02737-0https://doaj.org/toc/2041-1723A unified framework to understand gene expression noise is still lacking. Here the authors derive a universal theorem relating the biological noise with dynamics of birth and death processes and present a model of transcription dynamics, allowing analytical prediction of the dependence of mRNA noise on mRNA lifetime variability.Seong Jun ParkSanggeun SongGil-Suk YangPhilip M. KimSangwoon YoonJi-Hyun KimJaeyoung SungNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Seong Jun Park
Sanggeun Song
Gil-Suk Yang
Philip M. Kim
Sangwoon Yoon
Ji-Hyun Kim
Jaeyoung Sung
The Chemical Fluctuation Theorem governing gene expression
description A unified framework to understand gene expression noise is still lacking. Here the authors derive a universal theorem relating the biological noise with dynamics of birth and death processes and present a model of transcription dynamics, allowing analytical prediction of the dependence of mRNA noise on mRNA lifetime variability.
format article
author Seong Jun Park
Sanggeun Song
Gil-Suk Yang
Philip M. Kim
Sangwoon Yoon
Ji-Hyun Kim
Jaeyoung Sung
author_facet Seong Jun Park
Sanggeun Song
Gil-Suk Yang
Philip M. Kim
Sangwoon Yoon
Ji-Hyun Kim
Jaeyoung Sung
author_sort Seong Jun Park
title The Chemical Fluctuation Theorem governing gene expression
title_short The Chemical Fluctuation Theorem governing gene expression
title_full The Chemical Fluctuation Theorem governing gene expression
title_fullStr The Chemical Fluctuation Theorem governing gene expression
title_full_unstemmed The Chemical Fluctuation Theorem governing gene expression
title_sort chemical fluctuation theorem governing gene expression
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/453b0f4d9a3147b59f1f6680d93343c0
work_keys_str_mv AT seongjunpark thechemicalfluctuationtheoremgoverninggeneexpression
AT sanggeunsong thechemicalfluctuationtheoremgoverninggeneexpression
AT gilsukyang thechemicalfluctuationtheoremgoverninggeneexpression
AT philipmkim thechemicalfluctuationtheoremgoverninggeneexpression
AT sangwoonyoon thechemicalfluctuationtheoremgoverninggeneexpression
AT jihyunkim thechemicalfluctuationtheoremgoverninggeneexpression
AT jaeyoungsung thechemicalfluctuationtheoremgoverninggeneexpression
AT seongjunpark chemicalfluctuationtheoremgoverninggeneexpression
AT sanggeunsong chemicalfluctuationtheoremgoverninggeneexpression
AT gilsukyang chemicalfluctuationtheoremgoverninggeneexpression
AT philipmkim chemicalfluctuationtheoremgoverninggeneexpression
AT sangwoonyoon chemicalfluctuationtheoremgoverninggeneexpression
AT jihyunkim chemicalfluctuationtheoremgoverninggeneexpression
AT jaeyoungsung chemicalfluctuationtheoremgoverninggeneexpression
_version_ 1718383274218225664

Ejemplares similares