Catalytic mechanism of cellulose degradation by a cellobiohydrolase, CelS.

The hydrolysis of cellulose is the bottleneck in cellulosic ethanol production. The cellobiohydrolase CelS from Clostridium thermocellum catalyzes the hydrolysis of cello-oligosaccharides via inversion of the anomeric carbon. Here, to examine key features of the CelS-catalyzed reaction, QM/MM (SCCDF...

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Autores principales: Moumita Saharay, Hong Guo, Jeremy C Smith
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/45a92198666a401ebc56241ef8a7c440
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