Catalytic mechanism of cellulose degradation by a cellobiohydrolase, CelS.
The hydrolysis of cellulose is the bottleneck in cellulosic ethanol production. The cellobiohydrolase CelS from Clostridium thermocellum catalyzes the hydrolysis of cello-oligosaccharides via inversion of the anomeric carbon. Here, to examine key features of the CelS-catalyzed reaction, QM/MM (SCCDF...
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Main Authors: | , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/45a92198666a401ebc56241ef8a7c440 |
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