mDia1 senses both force and torque during F-actin filament polymerization

Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally unconstrained, suggesting that mDia1 can also sense...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Miao Yu, Xin Yuan, Chen Lu, Shimin Le, Ryo Kawamura, Artem K. Efremov, Zhihai Zhao, Michael M. Kozlov, Michael Sheetz, Alexander Bershadsky, Jie Yan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/45b944b61fe7413f8f71e13ac4d739be
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!