mDia1 senses both force and torque during F-actin filament polymerization

Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally unconstrained, suggesting that mDia1 can also sense...

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Autores principales:	Miao Yu, Xin Yuan, Chen Lu, Shimin Le, Ryo Kawamura, Artem K. Efremov, Zhihai Zhao, Michael M. Kozlov, Michael Sheetz, Alexander Bershadsky, Jie Yan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/45b944b61fe7413f8f71e13ac4d739be
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spelling	oai:doaj.org-article:45b944b61fe7413f8f71e13ac4d739be2021-12-02T15:38:57ZmDia1 senses both force and torque during F-actin filament polymerization10.1038/s41467-017-01745-42041-1723https://doaj.org/article/45b944b61fe7413f8f71e13ac4d739be2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01745-4https://doaj.org/toc/2041-1723Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally unconstrained, suggesting that mDia1 can also sense torque.Miao YuXin YuanChen LuShimin LeRyo KawamuraArtem K. EfremovZhihai ZhaoMichael M. KozlovMichael SheetzAlexander BershadskyJie YanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miao Yu Xin Yuan Chen Lu Shimin Le Ryo Kawamura Artem K. Efremov Zhihai Zhao Michael M. Kozlov Michael Sheetz Alexander Bershadsky Jie Yan mDia1 senses both force and torque during F-actin filament polymerization
description	Formins are actin-polymerisation factors that are sensitive to force. Here the authors find that pulling force on an actin filament promoted faster actin polymerisation by the formin mDia1, and also found that the actin filament must be torsionally unconstrained, suggesting that mDia1 can also sense torque.
format	article
author	Miao Yu Xin Yuan Chen Lu Shimin Le Ryo Kawamura Artem K. Efremov Zhihai Zhao Michael M. Kozlov Michael Sheetz Alexander Bershadsky Jie Yan
author_facet	Miao Yu Xin Yuan Chen Lu Shimin Le Ryo Kawamura Artem K. Efremov Zhihai Zhao Michael M. Kozlov Michael Sheetz Alexander Bershadsky Jie Yan
author_sort	Miao Yu
title	mDia1 senses both force and torque during F-actin filament polymerization
title_short	mDia1 senses both force and torque during F-actin filament polymerization
title_full	mDia1 senses both force and torque during F-actin filament polymerization
title_fullStr	mDia1 senses both force and torque during F-actin filament polymerization
title_full_unstemmed	mDia1 senses both force and torque during F-actin filament polymerization
title_sort	mdia1 senses both force and torque during f-actin filament polymerization
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/45b944b61fe7413f8f71e13ac4d739be
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mDia1 senses both force and torque during F-actin filament polymerization

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