Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

Summary: Transcription is a highly regulated sequence of stochastic processes utilizing many regulators, including nuclear receptors (NR) that respond to stimuli. Endocrine disrupting chemicals (EDCs) in the environment can compete with natural ligands for nuclear receptors to alter transcription. A...

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Autores principales: Michael J. Bolt, Pankaj Singh, Caroline E. Obkirchner, Reid T. Powell, Maureen G. Mancini, Adam T. Szafran, Fabio Stossi, Michael A. Mancini
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/45c83f8c8620468ca475b94663c889a3
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