Production of Noncapped Genomic RNAs Is Critical to Sindbis Virus Disease and Pathogenicity

ABSTRACT Alphaviruses are positive-sense RNA viruses that utilize a 5′ cap structure to facilitate translation of viral proteins and to protect the viral RNA genome. Nonetheless, significant quantities of viral genomic RNAs that lack a canonical 5′ cap structure are produced during alphaviral replic...

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Autores principales: Autumn T. LaPointe, V Douglas Landers, Claire E. Westcott, Kevin J. Sokoloski
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/45cab0136a9e4a81873d836c22da1439
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