Potentials of mean force for protein structure prediction vindicated, formalized and generalized.
Understanding protein structure is of crucial importance in science, medicine and biotechnology. For about two decades, knowledge-based potentials based on pairwise distances--so-called "potentials of mean force" (PMFs)--have been center stage in the prediction and design of protein struct...
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Main Authors: | Thomas Hamelryck, Mikael Borg, Martin Paluszewski, Jonas Paulsen, Jes Frellsen, Christian Andreetta, Wouter Boomsma, Sandro Bottaro, Jesper Ferkinghoff-Borg |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/45f90bfcdbad41b88281a3c31ce063c1 |
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