Microglia contact induces synapse formation in developing somatosensory cortex

Microglia contact induces synapse formation in developing somatosensory cortex

Microglia contribute to shaping neural circuits in the developing brain. Here, the authors show that microglial contact with pyramidal neuron dendrites induces synapse formation in the developing somatosensory cortex, and ablation of microglia reduces synaptic connections from L4 to L2/3 neurons.

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Autores principales: Akiko Miyamoto, Hiroaki Wake, Ayako Wendy Ishikawa, Kei Eto, Keisuke Shibata, Hideji Murakoshi, Schuichi Koizumi, Andrew J. Moorhouse, Yumiko Yoshimura, Junichi Nabekura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/45fff4d674a54f38b5ae086508a1e2b5
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https://doaj.org/article/45fff4d674a54f38b5ae086508a1e2b5

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