Multiplexed single-molecule force spectroscopy using a centrifuge

Single molecule force spectroscopy (SMFS) has limitations in throughput and the ability to repeatedly interrogate single bonds. Here the authors repurpose a benchtop centrifuge and use DNA nanoswitches to enable high throughput SMFS capable of repeatedly measuring forces of single molecular pairs.

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Detalles Bibliográficos
Autores principales: Darren Yang, Andrew Ward, Ken Halvorsen, Wesley P. Wong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/461600ab61c74653a81a639f445b8670
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