Multiplexed single-molecule force spectroscopy using a centrifuge

Single molecule force spectroscopy (SMFS) has limitations in throughput and the ability to repeatedly interrogate single bonds. Here the authors repurpose a benchtop centrifuge and use DNA nanoswitches to enable high throughput SMFS capable of repeatedly measuring forces of single molecular pairs.

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Detalles Bibliográficos
Autores principales:	Darren Yang, Andrew Ward, Ken Halvorsen, Wesley P. Wong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/461600ab61c74653a81a639f445b8670
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spelling	oai:doaj.org-article:461600ab61c74653a81a639f445b86702021-12-02T17:31:18ZMultiplexed single-molecule force spectroscopy using a centrifuge10.1038/ncomms110262041-1723https://doaj.org/article/461600ab61c74653a81a639f445b86702016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11026https://doaj.org/toc/2041-1723Single molecule force spectroscopy (SMFS) has limitations in throughput and the ability to repeatedly interrogate single bonds. Here the authors repurpose a benchtop centrifuge and use DNA nanoswitches to enable high throughput SMFS capable of repeatedly measuring forces of single molecular pairs.Darren YangAndrew WardKen HalvorsenWesley P. WongNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Darren Yang Andrew Ward Ken Halvorsen Wesley P. Wong Multiplexed single-molecule force spectroscopy using a centrifuge
description	Single molecule force spectroscopy (SMFS) has limitations in throughput and the ability to repeatedly interrogate single bonds. Here the authors repurpose a benchtop centrifuge and use DNA nanoswitches to enable high throughput SMFS capable of repeatedly measuring forces of single molecular pairs.
format	article
author	Darren Yang Andrew Ward Ken Halvorsen Wesley P. Wong
author_facet	Darren Yang Andrew Ward Ken Halvorsen Wesley P. Wong
author_sort	Darren Yang
title	Multiplexed single-molecule force spectroscopy using a centrifuge
title_short	Multiplexed single-molecule force spectroscopy using a centrifuge
title_full	Multiplexed single-molecule force spectroscopy using a centrifuge
title_fullStr	Multiplexed single-molecule force spectroscopy using a centrifuge
title_full_unstemmed	Multiplexed single-molecule force spectroscopy using a centrifuge
title_sort	multiplexed single-molecule force spectroscopy using a centrifuge
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/461600ab61c74653a81a639f445b8670
work_keys_str_mv	AT darrenyang multiplexedsinglemoleculeforcespectroscopyusingacentrifuge AT andrewward multiplexedsinglemoleculeforcespectroscopyusingacentrifuge AT kenhalvorsen multiplexedsinglemoleculeforcespectroscopyusingacentrifuge AT wesleypwong multiplexedsinglemoleculeforcespectroscopyusingacentrifuge
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Multiplexed single-molecule force spectroscopy using a centrifuge

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