Multiplexed single-molecule force spectroscopy using a centrifuge
Single molecule force spectroscopy (SMFS) has limitations in throughput and the ability to repeatedly interrogate single bonds. Here the authors repurpose a benchtop centrifuge and use DNA nanoswitches to enable high throughput SMFS capable of repeatedly measuring forces of single molecular pairs.
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Autores principales: | Darren Yang, Andrew Ward, Ken Halvorsen, Wesley P. Wong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/461600ab61c74653a81a639f445b8670 |
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