A threonyl-tRNA synthetase-mediated translation initiation machinery
The initiation of translation is a highly regulated process that contributes to specific gene expression programs. Here the authors find that, in vertebrate, threonyl-tRNA synthetase (TRS) can act as a scaffold for the initiation machinery to stimulate the translation of a specific set of mRNAs.
Guardado en:
Autores principales: | Seung Jae Jeong, Shinhye Park, Loi T. Nguyen, Jungwon Hwang, Eun-Young Lee, Hoi-Khoanh Giong, Jeong-Soo Lee, Ina Yoon, Ji-Hyun Lee, Jong Hyun Kim, Hoi Kyoung Kim, Doyeun Kim, Won Suk Yang, Seon-Young Kim, Chan Yong Lee, Kweon Yu, Nahum Sonenberg, Myung Hee Kim, Sunghoon Kim |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4626adc229bd48dc902ff7c0880575dc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction
por: Jong Hyun Kim, et al.
Publicado: (2017) -
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion
por: Wenlong Ding, et al.
Publicado: (2020) -
Structural Analysis of Glutamine Synthetase from Helicobacter pylori
por: Hyun Kyu Joo, et al.
Publicado: (2018) -
PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase
por: Gommaar D’Hulst, et al.
Publicado: (2020) -
Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics
por: Takaaki Akaike, et al.
Publicado: (2017)