Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes

Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes

Abstract γ-Aminobutyric acid type A (GABAA) receptors are pentameric GABA-gated chloride channels that are, in mammalians, drawn from a repertoire of 19 different genes, namely α1-6, β1-3, γ1-3, δ, ε, θ, π and ρ1-3. The existence of this wide variety of subunits as well as their diverse assembly int...

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Autores principales: Xenia Simeone, David C. B. Siebert, Konstantina Bampali, Zdravko Varagic, Marco Treven, Sabah Rehman, Jakob Pyszkowski, Raphael Holzinger, Friederike Steudle, Petra Scholze, Marko D. Mihovilovic, Michael Schnürch, Margot Ernst
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/46343707d7194d3e987086a53ab6033f
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https://doaj.org/article/46343707d7194d3e987086a53ab6033f

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