Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

Ageing is associated with a pronounced shift in mortality from cancer to degenerative diseases. Here, the authors show that in concordance with this shift, conserved transcriptional alterations during ageing across four vertebrates align with degenerative diseases but are opposite to those in cancer...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Jule Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W. Witte, Matthias Platzer, Eytan Ruppin, Christoph Kaleta
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/463f3bfceed14b74b71020ee1edcf215
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!