Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways.
A recent trend in drug development is to identify drug combinations or multi-target agents that effectively modify multiple nodes of disease-associated networks. Such polypharmacological effects may reduce the risk of emerging drug resistance by means of attacking the disease networks through synerg...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/464fb0e478384c6487cf3e21f71300fd |
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