Treatment of Severe Acute Pancreatitis and Related Lung Injury by Targeting Gasdermin D-Mediated Pyroptosis

The functional relevance and effects of the pyroptosis executioner gasdermin D (GSDMD) on severe acute pancreatitis (SAP)-associated lung injury are unclear. We established caerulein-induced mouse models of SAP-associated lung injury, which showed that GSDMD-mediated pyroptosis was activated in both...

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Bibliographic Details
Main Authors: Jinxiang Wu, Jintao Zhang, Jiping Zhao, Shihong Chen, Tao Zhou, Jianwei Xu
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/46512b7b269840048b5551bcdfe27463
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