How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome
The translation of mRNA by the ribosome is governed by a series of large-scale conformational transitions. Here the authors use MD simulations to demonstrate how the rate of dissociation of elongation factor Tu affects the dynamics of tRNA accommodation and proofreading.
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Main Authors: | Jeffrey K. Noel, Paul C. Whitford |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/4665a00df93a45c6bbfffb5f8957ae1c |
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