Exercise-induced changes in climbing performance
Exercise is recommended to promote health and prevent a range of diseases. However, how exercise precipitates these benefits is unclear, nor do we understand why exercise responses differ so widely between individuals. We investigate how climbing ability in Drosophila melanogaster changes in respons...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
The Royal Society
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/46884ed9026f44abb57dc7d7daefb154 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
| id |
oai:doaj.org-article:46884ed9026f44abb57dc7d7daefb154 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:46884ed9026f44abb57dc7d7daefb1542021-11-10T08:06:33ZExercise-induced changes in climbing performance10.1098/rsos.2112752054-5703https://doaj.org/article/46884ed9026f44abb57dc7d7daefb1542021-11-01T00:00:00Zhttps://royalsocietypublishing.org/doi/10.1098/rsos.211275https://doaj.org/toc/2054-5703Exercise is recommended to promote health and prevent a range of diseases. However, how exercise precipitates these benefits is unclear, nor do we understand why exercise responses differ so widely between individuals. We investigate how climbing ability in Drosophila melanogaster changes in response to an exercise treatment. We find extensive variation in baseline climbing ability and exercise-induced changes ranging from −13% to +20% in climbing ability. Climbing ability, and its exercise-induced change, is sex- and genotype-dependent. GWASs implicate ‘cell–cell signalling’ genes in the control of climbing ability. We also find that animal activity does not predict climbing ability and that the exercise-induced climbing ability change cannot be predicted from the activity level induced by the exercise treatment. These results provide promising new avenues for further research into the molecular pathways controlling climbing activity and illustrate the complexities involved in trying to predict individual responses to exercise.Louis P. WatanabeNicole C. RiddleThe Royal SocietyarticleDrosophilaphysical fitnessclimbingexerciseDGRPGWASScienceQENRoyal Society Open Science, Vol 8, Iss 11 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Drosophila physical fitness climbing exercise DGRP GWAS Science Q |
| spellingShingle |
Drosophila physical fitness climbing exercise DGRP GWAS Science Q Louis P. Watanabe Nicole C. Riddle Exercise-induced changes in climbing performance |
| description |
Exercise is recommended to promote health and prevent a range of diseases. However, how exercise precipitates these benefits is unclear, nor do we understand why exercise responses differ so widely between individuals. We investigate how climbing ability in Drosophila melanogaster changes in response to an exercise treatment. We find extensive variation in baseline climbing ability and exercise-induced changes ranging from −13% to +20% in climbing ability. Climbing ability, and its exercise-induced change, is sex- and genotype-dependent. GWASs implicate ‘cell–cell signalling’ genes in the control of climbing ability. We also find that animal activity does not predict climbing ability and that the exercise-induced climbing ability change cannot be predicted from the activity level induced by the exercise treatment. These results provide promising new avenues for further research into the molecular pathways controlling climbing activity and illustrate the complexities involved in trying to predict individual responses to exercise. |
| format |
article |
| author |
Louis P. Watanabe Nicole C. Riddle |
| author_facet |
Louis P. Watanabe Nicole C. Riddle |
| author_sort |
Louis P. Watanabe |
| title |
Exercise-induced changes in climbing performance |
| title_short |
Exercise-induced changes in climbing performance |
| title_full |
Exercise-induced changes in climbing performance |
| title_fullStr |
Exercise-induced changes in climbing performance |
| title_full_unstemmed |
Exercise-induced changes in climbing performance |
| title_sort |
exercise-induced changes in climbing performance |
| publisher |
The Royal Society |
| publishDate |
2021 |
| url |
https://doaj.org/article/46884ed9026f44abb57dc7d7daefb154 |
| work_keys_str_mv |
AT louispwatanabe exerciseinducedchangesinclimbingperformance AT nicolecriddle exerciseinducedchangesinclimbingperformance |
| _version_ |
1718440368016457728 |