Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria
The absence of effective gene activators in bacteria limits regulated expression programs. Here the authors design synthetic bacterial CRISPR-Cas transcriptional activators that can be used to construct multi-gene programs of activation and repression.
Guardado en:
Autores principales: | Chen Dong, Jason Fontana, Anika Patel, James M. Carothers, Jesse G. Zalatan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4698bcb289ae4ad39b0b62c50044470c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Author Correction: Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria
por: Chen Dong, et al.
Publicado: (2018) -
Effective CRISPRa-mediated control of gene expression in bacteria must overcome strict target site requirements
por: Jason Fontana, et al.
Publicado: (2020) -
Human pluripotent reprogramming with CRISPR activators
por: Jere Weltner, et al.
Publicado: (2018) -
Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia
por: Francis P. Pankowicz, et al.
Publicado: (2016) -
CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice
por: Most Sumona Akter, et al.
Publicado: (2021)