Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis
In breast cancer, the loss of expression of WW domain-containing oxireductase (Wwox) has been observed. Here, the authors illustrate that in triple negative breast cancer models Wwox suppresses metastasis and proliferation via the JAK2/STAT3 pathway.
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/46a1268fb89a419cb3100d7ee1428ee9 |
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