MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging
miR-34 is known to regulate age-related gene expression in the Drosophila brain, and miR-34 overexpression can attenuate neurodegeneration induced by polyQ-expanded proteins. Here, Kennerdell and colleagues show that miR-34 confers longevity and neuroprotection via an epigenetic regulator Polycomb R...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2018
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/46b18f5ce1f94082bae17081ac9c2d7d |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|