Surface Export of GAPDH/SDH, a Glycolytic Enzyme, Is Essential for <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Virulence

ABSTRACT Streptococcal surface dehydrogenase (SDH) (glyceraldehyde-3-phosphate dehydrogenase [GAPDH]) is an anchorless major multifunctional surface protein in group A Streptococcus (GAS) with the ability to bind important mammalian proteins, including plasmin(ogen). Although several biological prop...

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Autores principales: Hong Jin, Shivangi Agarwal, Shivani Agarwal, Vijay Pancholi
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/475bd77e75094422b3ec7a7b0060a654
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