The quantitative metabolome is shaped by abiotic constraints

Evolution selects for the fittest but must operate within the realm of the physically possible. Here, the authors present a theoretical framework that allows them to explore how ten abiotic constraints can shape the operation, regulation, and adaptation of metabolism in E. coli.

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Detalles Bibliográficos
Autores principales:	Amir Akbari, James T. Yurkovich, Daniel C. Zielinski, Bernhard O. Palsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/47788bcb4646471292db38ad57312462
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id	oai:doaj.org-article:47788bcb4646471292db38ad57312462
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spelling	oai:doaj.org-article:47788bcb4646471292db38ad573124622021-12-02T14:42:19ZThe quantitative metabolome is shaped by abiotic constraints10.1038/s41467-021-23214-92041-1723https://doaj.org/article/47788bcb4646471292db38ad573124622021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23214-9https://doaj.org/toc/2041-1723Evolution selects for the fittest but must operate within the realm of the physically possible. Here, the authors present a theoretical framework that allows them to explore how ten abiotic constraints can shape the operation, regulation, and adaptation of metabolism in E. coli.Amir AkbariJames T. YurkovichDaniel C. ZielinskiBernhard O. PalssonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amir Akbari James T. Yurkovich Daniel C. Zielinski Bernhard O. Palsson The quantitative metabolome is shaped by abiotic constraints
description	Evolution selects for the fittest but must operate within the realm of the physically possible. Here, the authors present a theoretical framework that allows them to explore how ten abiotic constraints can shape the operation, regulation, and adaptation of metabolism in E. coli.
format	article
author	Amir Akbari James T. Yurkovich Daniel C. Zielinski Bernhard O. Palsson
author_facet	Amir Akbari James T. Yurkovich Daniel C. Zielinski Bernhard O. Palsson
author_sort	Amir Akbari
title	The quantitative metabolome is shaped by abiotic constraints
title_short	The quantitative metabolome is shaped by abiotic constraints
title_full	The quantitative metabolome is shaped by abiotic constraints
title_fullStr	The quantitative metabolome is shaped by abiotic constraints
title_full_unstemmed	The quantitative metabolome is shaped by abiotic constraints
title_sort	quantitative metabolome is shaped by abiotic constraints
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/47788bcb4646471292db38ad57312462
work_keys_str_mv	AT amirakbari thequantitativemetabolomeisshapedbyabioticconstraints AT jamestyurkovich thequantitativemetabolomeisshapedbyabioticconstraints AT danielczielinski thequantitativemetabolomeisshapedbyabioticconstraints AT bernhardopalsson thequantitativemetabolomeisshapedbyabioticconstraints AT amirakbari quantitativemetabolomeisshapedbyabioticconstraints AT jamestyurkovich quantitativemetabolomeisshapedbyabioticconstraints AT danielczielinski quantitativemetabolomeisshapedbyabioticconstraints AT bernhardopalsson quantitativemetabolomeisshapedbyabioticconstraints
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The quantitative metabolome is shaped by abiotic constraints

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