Plasma triacylglycerols are biomarkers of β-cell function in mice and humans

Plasma triacylglycerols are biomarkers of β-cell function in mice and humans

Objectives: To find plasma biomarkers prognostic of type 2 diabetes, which could also inform on pancreatic β-cell deregulations or defects in the function of insulin target tissues. Methods: We conducted a systems biology approach to characterize the plasma lipidomes of C57Bl/6J, DBA/2J, and BALB/cJ...

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Autores principales: Ana Rodríguez Sánchez-Archidona, Céline Cruciani-Guglielmacci, Clara Roujeau, Leonore Wigger, Justine Lallement, Jessica Denom, Marko Barovic, Nadim Kassis, Florence Mehl, Jurgen Weitz, Marius Distler, Christian Klose, Kai Simons, Mark Ibberson, Michele Solimena, Christophe Magnan, Bernard Thorens
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Triacylglycerols
β-cell function
Systems biology
Type 2 diabetes
PITPNC1
Biomarkers
Internal medicine
RC31-1245
Acceso en línea:https://doaj.org/article/477a61cb926a45169eb295d1b2333bc1
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https://doaj.org/article/477a61cb926a45169eb295d1b2333bc1

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