TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

Epigenetic regulators contribute to the modulation of adipose thermogenesis by sensing environmental cues and regulating gene expression in response. Here the authors report that a DNA demethylase TET1 mediates epigenetic changes to repress thermogenic genes in mouse adipose tissue.

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Autores principales: Sneha Damal Villivalam, Dongjoo You, Jinse Kim, Hee Woong Lim, Han Xiao, Pete-James H. Zushin, Yasuo Oguri, Pouya Amin, Sona Kang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4797aed5ec144f80886437b84bb7f261
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