TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

Epigenetic regulators contribute to the modulation of adipose thermogenesis by sensing environmental cues and regulating gene expression in response. Here the authors report that a DNA demethylase TET1 mediates epigenetic changes to repress thermogenic genes in mouse adipose tissue.

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Autores principales:	Sneha Damal Villivalam, Dongjoo You, Jinse Kim, Hee Woong Lim, Han Xiao, Pete-James H. Zushin, Yasuo Oguri, Pouya Amin, Sona Kang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4797aed5ec144f80886437b84bb7f261
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spelling	oai:doaj.org-article:4797aed5ec144f80886437b84bb7f2612021-12-02T15:09:18ZTET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis10.1038/s41467-020-18054-y2041-1723https://doaj.org/article/4797aed5ec144f80886437b84bb7f2612020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18054-yhttps://doaj.org/toc/2041-1723Epigenetic regulators contribute to the modulation of adipose thermogenesis by sensing environmental cues and regulating gene expression in response. Here the authors report that a DNA demethylase TET1 mediates epigenetic changes to repress thermogenic genes in mouse adipose tissue.Sneha Damal VillivalamDongjoo YouJinse KimHee Woong LimHan XiaoPete-James H. ZushinYasuo OguriPouya AminSona KangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sneha Damal Villivalam Dongjoo You Jinse Kim Hee Woong Lim Han Xiao Pete-James H. Zushin Yasuo Oguri Pouya Amin Sona Kang TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
description	Epigenetic regulators contribute to the modulation of adipose thermogenesis by sensing environmental cues and regulating gene expression in response. Here the authors report that a DNA demethylase TET1 mediates epigenetic changes to repress thermogenic genes in mouse adipose tissue.
format	article
author	Sneha Damal Villivalam Dongjoo You Jinse Kim Hee Woong Lim Han Xiao Pete-James H. Zushin Yasuo Oguri Pouya Amin Sona Kang
author_facet	Sneha Damal Villivalam Dongjoo You Jinse Kim Hee Woong Lim Han Xiao Pete-James H. Zushin Yasuo Oguri Pouya Amin Sona Kang
author_sort	Sneha Damal Villivalam
title	TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
title_short	TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
title_full	TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
title_fullStr	TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
title_full_unstemmed	TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
title_sort	tet1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4797aed5ec144f80886437b84bb7f261
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TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

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