Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts
Abstract Connective tissue growth factor (CTGF) associated with transforming growth factor-β (TGF-β) play a pivotal role in the pathophysiology of many fibrotic disorders. However, it is not clear whether this interaction also takes place in GO. In this study, we investigated the role of CTGF in TGF...
Saved in:
Main Authors: | Chieh-Chih Tsai, Shi-Bei Wu, Hui-Chuan Kau, Yau-Huei Wei |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/47e4d2ecb6554644b05f12275d537fdc |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Nitric oxide attenuated transforming growth factor-β induced myofibroblast differentiation of human keratocytes
by: Joo-Hee Park, et al.
Published: (2021) -
The production of fibroblast growth factor 23 is controlled by TGF-β2
by: Martina Feger, et al.
Published: (2017) -
Mimicking Paracrine TGFβ1 Signals during Myofibroblast Differentiation in 3D Collagen Networks
by: Michael Ansorge, et al.
Published: (2017) -
Cytokine and Complement Response in the Glaucomatous βB1-CTGF Mouse Model
by: Sabrina Reinehr, et al.
Published: (2021) -
Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-β signaling.
by: Liang Wu, et al.
Published: (2014)