Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells

Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells

ABSTRACT Although most seasonal inactivated influenza vaccines (IIV) contain neuraminidase (NA), the extent and mechanisms of action of protective human NA-specific humoral responses induced by vaccination are poorly resolved. Due to the propensity of influenza virus for antigenic drift and shift an...

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Autores principales: Michael S. Piepenbrink, Aitor Nogales, Madhubanti Basu, Christopher F. Fucile, Jane L. Liesveld, Michael C. Keefer, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
B cell responses
human
influenza vaccines
monoclonal antibodies
neuraminidase
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/486dc477ed854784addaf977de56a6bc
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https://doaj.org/article/486dc477ed854784addaf977de56a6bc

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