Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota

The coevolution of the animal gut mucosa and the gut microbiota is poorly understood. Here, Nakashima et al. identify intestinal chitinous membranes in basal chordates and ray-finned fish, and propose that the loss of this chitin barrier allowed mucus layers to become colonized by microbes in mammal...

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Autores principales: Keisuke Nakashima, Satoshi Kimura, Yu Ogawa, Soichi Watanabe, Satoshi Soma, Toyoji Kaneko, Lixy Yamada, Hitoshi Sawada, Che-Huang Tung, Tsai-Ming Lu, Jr-Kai Yu, Alejandro Villar-Briones, Sakura Kikuchi, Noriyuki Satoh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/48b3204bc18a4060ae3215c178930765
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