Suppression of multiple myeloma by mitochondrial targeting

Abstract Treatment of multiple myeloma (MM) aims at inducing cell apoptosis by surpassing the limited capacity of MM cells to cope with oxidative stress. MM cell survival may further be suppressed by limiting cellular cholesterol. Long-chain fatty acid analogs of the MEDICA series promote mitochondr...

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Auteurs principaux: Yana Aisen, Moshe E. Gatt, Rachel Hertz, Elia Smeir, Jacob Bar-Tana
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/48da890086fd45d8856e963201073334
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