Circulating CD40 and sCD40L Predict Changes in Renal Function in Subjects with Chronic Kidney Disease

Circulating CD40 and sCD40L Predict Changes in Renal Function in Subjects with Chronic Kidney Disease

Abstract Soluble CD40 ligand (sCD40L) has been implicated in the development of renal injury. The CD40 receptor exists in a soluble form, sCD40R, and has been shown to function as a competitive antagonist against CD40 activation. We analyzed whether plasma levels of sCD40L and sCD40R predict changes...

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Main Authors: Jeffrey X. Xie, Helen Alderson, James Ritchie, Philip A. Kalra, Yanmei Xie, Kaili Ren, Hanh Nguyen, Tian Chen, Pamela Brewster, Rajesh Gupta, Lance D. Dworkin, Deepak Malhotra, Christopher J. Cooper, Jiang Tian, Steven T. Haller
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/48f5f24ffe304226aa5bceacf2bedcf1
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