Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life

The sulfur-reducing enzyme MBS and the hydrogen-gas evolving MBH are the evolutionary link between the ancestor Mrp antiporter and the mitochondrial respiratory complex I. Here, the authors characterise MBS from the hyperthermophilic archaeon Pyrococcus furiosus, solve its cryo-EM structure and disc...

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Autores principales: Hongjun Yu, Dominik K. Haja, Gerrit J. Schut, Chang-Hao Wu, Xing Meng, Gongpu Zhao, Huilin Li, Michael W. W. Adams
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/48f8c0525140486e964bdeb38e02a289
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