Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations

Yang et al. examine whether genetic ancestry is associated with genetic variation in fatty acid desaturases and plasma phospholipid levels of long chain polyunsaturated fatty acids (LC-PUFAs) in Hispanic Americans. They find strong associations between Amerind genetic ancestry and LC-PUFA levels; an...

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Autores principales: Chaojie Yang, Brian Hallmark, Jin Choul Chai, Timothy D. O’Connor, Lindsay M. Reynolds, Alexis C. Wood, Michael Seeds, Yii-Der Ida Chen, Lyn M. Steffen, Michael Y. Tsai, Robert C. Kaplan, Martha L. Daviglus, Lawrence J. Mandarino, Amanda M. Fretts, Rozenn N. Lemaitre, Dawn K. Coletta, Sarah A. Blomquist, Laurel M. Johnstone, Chandra Tontsch, Qibin Qi, Ingo Ruczinski, Stephen S. Rich, Rasika A. Mathias, Floyd H. Chilton, Ani Manichaikul
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/490453d6665243aba801e3d3ea7f205f
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