ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

Acetyl-CoA carboxylases ACC1 and ACC2 catalyze the carboxylation of acetyl-CoA to malonyl-CoA, regulating fatty-acid synthesis and oxidation, and are potential targets for treatment of metabolic syndrome. Expression of ACC1 in rodent lipogenic tissues and ACC2 in rodent oxidative tissues, coupled wi...

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Autores principales: John C Castle, Yoshikazu Hara, Christopher K Raymond, Philip Garrett-Engele, Kenji Ohwaki, Zhengyan Kan, Jun Kusunoki, Jason M Johnson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/4970341b1eab4e9283fe1ceb74f92e09
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