Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines
ABSTRACT Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens. We showed, through use of a CRISPR-Cas9 CD40 knockout, that the superantigens to...
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| Main Authors: | Patrick M. Schlievert, Michael P. Cahill, Bruce S. Hostager, Amanda J. Brosnahan, Aloysius J. Klingelhutz, Francoise A. Gourronc, Gail A. Bishop, Donald Y. M. Leung |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/49782844522c4c8c856aa6a48efa7298 |
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