TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

Interferons have been shown to mediate tumour rejection. Here, in a spontaneous mouse model of breast cancer, the authors show that this is disrupted owing to high levels of TGFβ produced in the tumour.

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Detalles Bibliográficos
Autores principales: Marion V. Guerin, Fabienne Regnier, Vincent Feuillet, Lene Vimeux, Julia M. Weiss, Georges Bismuth, Gregoire Altan-Bonnet, Thomas Guilbert, Maxime Thoreau, Veronica Finisguerra, Emmanuel Donnadieu, Alain Trautmann, Nadège Bercovici
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/4998cfedc6d240aeaec2f8249ea1a3ed
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https://doaj.org/article/4998cfedc6d240aeaec2f8249ea1a3ed

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