Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis.

Visceral leishmaniasis (VL) is a vector-borne disease affecting humans and domestic animals that constitutes a serious public health problem in many countries. Although many antigens have been examined so far as protein- or DNA-based vaccines, none of them conferred complete long-term protection. Th...

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Main Authors: Noushin Saljoughian, Tahereh Taheri, Farnaz Zahedifard, Yasaman Taslimi, Fatemeh Doustdari, Azam Bolhassani, Delaram Doroud, Hiva Azizi, Kazem Heidari, Mohammad Vasei, Nabiollah Namvar Asl, Barbara Papadopoulou, Sima Rafati
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/499954bbfcd346d18bbb91fe41e99e56
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