Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC
The Legionella effector MavC catalyses the ubiquitination of the E2 enzyme UBE2N in the host cell through a transglutamination reaction, which can be inhibited by the Legionella effector Lpg2149. Here, the authors provide mechanistic insights into these processes by determining the crystal structure...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/49c5000932d54e70b56ba771b5e61c22 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|