Central dogma rates and the trade-off between precision and economy in gene expression

The same protein abundance can be achieved by many combinations of transcription, translation and degradation rates. Here, the authors find that genes combining high transcription with low translation rate are rare due to a trade-off between the cost of transcription and expression noise.

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Detalles Bibliográficos
Autores principales: Jean Hausser, Avi Mayo, Leeat Keren, Uri Alon
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/49c76385217d4abdbed2391068e344b2
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