Molecular basis of AKAP79 regulation by calmodulin
The A-kinase anchoring protein AKAP79 is regulated by calmodulin (CaM). Here, the authors use crosslinking coupled to mass spectrometry to identify the CaM-binding site in AKAP79 and present the structure of CaM bound to an AKAP79 peptide. The structure shows that CaM adopts a highly compact conform...
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Autores principales: | Neha Patel, Florian Stengel, Ruedi Aebersold, Matthew G. Gold |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/49cdec22e2cc46518168ece42a2d109f |
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