Ursodeoxycholic Acid Attenuates the Retinal Vascular Abnormalities in Anti-PDGFR-β Antibody-Induced Pericyte Depletion Mouse Models

Abstract As a clinical manifestations of diabetic retinopathy (DR), pericytes (PCs) loss from the capillary walls is thought to be an initial pathological change responsible for the breakdown of the blood-retinal barrier (BRB). This study was performed to investigate the effects of ursodeoxycholic a...

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Autores principales: Tomoyasu Shiraya, Fumiyuki Araki, Takashi Ueta, Hisako Fukunaga, Kiyohito Totsuka, Takahiro Arai, Akiyoshi Uemura, Kyoji Moriya, Satoshi Kato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/49dd9235874a46388ff3d093524a0bf7
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