A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis
The integral membrane protein Apq12 is an important nuclear envelope (NE)/endoplasmic reticulum (ER) modulator that cooperates with the nuclear pore complex (NPC) biogenesis factors Brl1 and Brr6. How Apq12 executes these functions is unknown. Here, we identified a short amphipathic α-helix (AαH) in...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
The Royal Society
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/49f2b3970e5e42359e25debff6fe7f98 |
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